BOC Sciences is able to provide a variety of microbial fermentation services using Bacillus subtilis as host cells, such as improving strains metabolism, transforming primitive strains into industrialized strains, developing microbial fermentation process, fermentation scale-up, etc. Due to our complete strain development platform and extensive experience in microbial production, we can offer one-stop fermentation services ranging from laboratory fermentation to large-scale microbial manufacturing. Bacillus subtilis fermentation is one of the most widely studied bacteria and can serve as a cell factory for industrial production, including enzymes and proteins. Thus, our Bacillus subtilis system can help our customers to achieve industrial-scale fermentation economically.
Introduction of B. subtilis
Bacillus subtilis, abbreviated as B. subtilis, is a Gram-positive, peroxidase-positive bacterium primarily found in soil and vegetation, named by Ferdinand Cohn in 1872. B. subtilis is considered to be a facultative anaerobe. The cellular structure of B. subtilis is usually rod-shaped, and the optimal growth temperature is 25-35 ℃, but they can also withstand extreme environmental conditions up to 80 ℃. Furthermore, B. subtilis contain approximately 4100 genes, 192 are indispensable, and 79 are predicted to be essential. The vast majority of essential genes are classified in the cellular metabolism domain. B. subtilis has proven to be well suited as a laboratory model organism for genetic research, and is widely used to study cell differentiation and bacterial chromosome replication.
Advantages of B. subtilis Fermentation
Application of B. subtilis Fermentation
Project Workflow of B. subtilis Fermentation
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